Two Texas women explain how drugs like the type 2 diabetes drugs Mounjaro and Ozempic helped ease symptoms of PCOS or polycystic ovary syndrome
Two Texas women are opening up about taking the type 2 diabetes drug Mounjaro to help their symptoms of PCOS, or polycystic ovary syndrome.
He spoke to Tiffany Groves, 38 Good morning America that he struggled for a decade after being diagnosed with PCOS, a hormonal imbalance that affects 1 in 10 women of childbearing age. The condition can cause symptoms such as irregular periods, excessive hair growth, acne, weight gain, and infertility.
In October 2022, Groves learned about Mounjaro on social media and began taking the drug off-label for his PCOS symptoms. Mounjaro is an FDA-approved prescription drug for people with type 2 diabetes. It is a brand name for tirzepatide, which has been shown to be very effective for weight loss by reducing appetite and improving the way the body breaks it down. sugars and fats.
Mounjaro is similar to the Ozempic and Wegovy brand names for semaglutide that works in the brain to affect satiety, and all three drugs have been trending in Hollywood weight-loss circles.
Groves told the outlet that after taking the drug, he quickly lost 43 pounds. and began experiencing regular menstrual cycles for the first time in his life.
“All this time I’ve been living life and I thought it was normal to think about food all the time and then all of a sudden you don’t think about food,” she said. “I can just eat a little and be perfectly fine.”
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Dr. Rekha Kumar, an endocrinologist at Weill Cornell Medicine and NewYork-Presbyterian and an expert on obesity and PCOS, told the outlet that these medications can help with insulin resistance, a health issue that can be caused by the condition.
“It’s not necessarily that we’re using drugs to treat PCOS, but drugs may be helpful for one of the symptoms of PCOS, which is the actual weight gain and hormonal drive to eat carbohydrates due to insulin resistance” Kumar explained. . “What we’ve learned over the past 20 years is that PCOS is actually a carbohydrate-insulin metabolism problem called insulin resistance, which means that the body produces more insulin in response to carbohydrates.
She continued, “And what people often forget about insulin is that it’s a hormone that promotes fat storage, so the more insulin your body is producing, the better off you are at storing fat.”
Plus, Branneisha Cooper, 26, said GMA extension who started taking Mounjaro in November 2022 after being diagnosed with PCOS when she was in high school. Since then she has lost more than 40 pounds, has experienced a reduction in inflammation and has a regular menstrual cycle.
“[My doctor] she said, “There’s this amazing drug, and I already have a couple of women who have PCOS as well,” she recalled. “Ever since I started on Mounjaro, it’s honestly just been like a stress reliever. I feel like a weight has been lifted off my shoulders.”
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“Before taking this drug, I thought it was just a personal issue, that there was just something I couldn’t figure out that other people were,” Cooper said at the outlet. “It wasn’t until I [went] on Mounjaro and realized it’s a chronic disease… and you weren’t the problem.”
Cooper stressed that taking the drug is more than just weight loss for me as she is now hoping to get pregnant after years of dealing with PCOS related infertility.
Kumar noted a GMA extension that because many women with PCOS deal with infertility, it’s important that they avoid using Mounjaro, Ozempic, and Wegovy while pregnant or trying to get pregnant.
“We just need to really make sure that patients understand the risks and unknowns of getting pregnant on these meds, because when we treat people with insulin resistance, they become more fertile,” Kumar said at the outlet. “Women who thought they could never get pregnant, if you’re treating them on these meds, they might, so we just need to be very careful about educating about the risks.”
The FDA said in a report that there is insufficient data on the effects of these drugs on pregnant patients. However, women are advised to avoid its use during pregnancy. The agency states that “weight loss offers no benefit to a pregnant patient and may cause harm to the fetus” and that pregnant women should stop using the drugs at least two months before a planned pregnancy.
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